Description
BIOMOX® (amoxicillin) is a broad-spectrum,
semisynthetic antibiotic which provides bactericidal activity against a wide
range of common gram-positive and gram-negative pathogens. Amoxicillin
chemically is D-(-)a-amino-p-hydroxybenzyl penicillin trihydrate.
Inactive Ingredients
Dibasic Calcium Phosphate Dihydrate, Magnesium Stearate,
Microcrystalline Cellulose and Sodium Starch Glycolate.
ACTION:
Amoxicillin has bactericidal activity against susceptible
organisms similar to that of ampicillin. It acts by inhibiting the biosynthesis
of bacterial cell wall mucopeptides. Most strains of the following
gram-positive and gram-negative bacteria have demonstrated susceptibility to
amoxicillin, both in vitro and in vivo nonpenicillinase-producing
staphylococci, alpha- and beta-hemolytic streptococci, Streptococcus
faecalis, Escherichia coli and Proteus mirabilis. Amoxicillin does
not resist destruction by penicillinase; therefore, it is not effective against
penicillinase-producing bacteria, particularly resistant staphylococci. Most
strains of Enterobacter and Klebsiella and all strains of Pseudomonas
are resistant.
Amoxicillin may be given without regard to meals because
it is stable in gastric acid. It is rapidly absorbed following oral
administration and diffuses readily into most body fluids and tissues. It
diffuses poorly into the brain and spinal fluid except when the meninges are
inflamed. Most of amoxicillin is excreted in the urine unchanged.
Biomox Tablets Indications
BIOMOX® (amoxicillin) tablets are indicated in
the treatment of the following infections in dogs when caused by susceptible
strains of organisms:
BACTERIAL DERMATITIS due to Staphylococcus aureus,
Streptococcus spp., Staphylococcus spp. and E. coli.
SOFT TISSUE INFECTIONS (abscesses, wounds, lacerations)
due to Staphylococcus aureus, Streptococcus spp., E. coli, Proteus mirabilis
and Staphylococcus spp.
As is true with all antibiotic therapy, appropriate in
vitro cultures and sensitivities should be conducted prior to treatment.
Contraindications
The use of amoxicillin is contraindicated in animals with
a history of an allergic reaction to penicillin.
Adverse Reactions
Amoxicillin is a semisynthetic penicillin and, therefore,
has the potential for producing allergic reactions. Epinephrine and/or steroids
should be administered if an allergic reaction occurs.
Warnings
For use in dogs only.
Precautions
Until adequate reproductive studies are accomplished,
Biomox® (amoxicillin) tablets should not be used in pregnant or
breeding animals.
Biomox Tablets Caution
Federal law restricts this drug to use by or on the order
of a licensed veterinarian.
Dosage and Administration
The recommended dosage is 5 mg per pound of body weight
administered twice daily for 5 to 7 days or 48 hours after all symptoms have
subsided. If no improvement is noted in 5 days, the diagnosis should be
reconsidered and therapy changed.
SUPPLY:
Biomox® (amoxicillin) tablets are supplied in
50 mg, 100 mg and 200 mg concentrations in bottles of 500 tablets.
Bulk Container - Not for Household Dispensing.
Store at controlled room temperature between 15° and 30°C
(59°F and 86°F).