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Heartgard Plus Chewables

Prescription Required
From $5.09


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Up to 25lb

Select your product options above to view the stock and delivery information.


Select your product options above to view the stock and delivery information.


Select your product options above to view the stock and delivery information.

All medications are filled by Pet's Choice Pharmacy. More information. Can only be shipped in the United States.
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Product Summary:

Prescription items are NON-RETURNABLE and NON REFUNDABLE

HEARTGARD Plus Chewables for Canines

HEARTGARD Plus for dogs is a beef-flavored soft chew administered once a month to protect your dog from the threat of potentially deadly heartworm disease, plus control against roundworms and hookworms. Dogs six months of age and older should be tested for heartworm disease prior to being put on a preventive program and tested annually thereafter.

Item Specifications:

HEARTGARD Plus is used to prevent heartworm disease, treat, and control roundworms and hookworms.

For Use:
Dogs (at least 6 weeks of age)

SM (Blue) for dogs up to 25 lb.
MD (Blue) for dogs 26-50 lb.
LG (Brown) for dogs 51-100 lb.

Active Ingredients:
Ivermectin, pyrantel

Make sure to tell your veterinarian what other medication you are giving to your pet. Quite often your veterinarian may prescribe two different medications, and a drug interaction may be anticipated. In this case, your veterinarian may vary the dose and/or monitor your pet more closely. The following drugs can potentially interact with pyrantel pamoate: levamisole, organophosphates, diethylcarbamazine, and piperazine. Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together. Certain dogs of the collie breed are more sensitive to the effects of ivermectin. Allergic reactions to medications may occur. If your pet displays symptoms of an allergic reaction, call your veterinarian immediately or go to a veterinary emergency clinic. Symptoms may include but are not limited to: swollen lips, tongue, face, airways; difficulty breathing; agitation; profuse salivation; vomiting; widespread hives and itching.

Side Effects:
There are very few side effects when the drug is given at the usual dose. Ivermectin may cause a shock like reaction in dogs. If this occurs, notify your veterinarian. Vomiting has been reported with pyrantel. Other side effects may occur. If you notice anything unusual, contact your veterinarian.

HEARTGARD Plus should be given orally as directed by your veterinarian.

Style Item Number Model Number UPC
51-100lbs 12 Month 496975 LG 12CT 012MAC03-51-100 350604401438
51-100lbs 1 Count 496975 LG 1CT 012MAC01-51-100-CHEW
51-100lbs 6 Month 496975 LG 6CT 012MAC-272 350604401414
26-50lbs 12 Month 496975 MD 12CT 012MAC03-26-50 350604401339
26-50lbs 1 Count 496975 MD 1CT 012MAC01-26-50-CHEW
26-50lbs 6 Month 496975 MD 6CT 012MAC0126-50 350604401315
Up to 25lb 12 Month 496975 SM 12CT 012MAC03-0-25 350604401230
Up to 25lb 1 Count 496975 SM 1CT 012MAC01-5-25-CHEW
Up to 25lb 6 Month 496975 SM 6CT 012MAC01-5-25 350604401216
Additional Information:

Please Note: 

This prescription product or therapeutic food is fulfilled by Pet’s Choice Pharmacy, Inc. A licensed pharmacy in all states, excluding North Carolina. Pet’s Choice is working with North Carolina Board of Pharmacy to be licensed to fill prescriptions in the future. We are only authorized to ship within the United States.  

To order prescription products or therapeutic foods must have an existing, valid veterinarian-client-patient relationship.  Prescription requests are subject to a Drug Utilization Review by a licensed pharmacist for patient safety. By law we can only accept a prescription faxed from your veterinarian or we must have the original prescription.

All prescription products (excluding therapeutic food) are FDA approved, or EPA licensed, to be sold in the US. Prescription products cannot be returned.  

Are we a licensed pharmacy?

The National Association of Boards of Pharmacy (NABP) has approved us as a Safe Site through its .pharmacy verified website program. We are not a licensed pharmacy; however, we are permitted to display pet medications on our site and have prescription orders fulfilled and delivered through our trusted partner, Pet’s Choice Pharmacy, an NABP .pharmacy verified website. This gives you a trusted and affordable alternative to purchase the medications your beloved pets need to maintain quality of life and overall health.

The .Pharmacy Verified program, prior to approval of domain registration, ensures that applicants meet all applicable Program Standards, which address regulatory standards including; to be licensed, registered, or hold appropriate permits where it is headquartered and where its customers reside, to protect patient medical and financial information and to have a clean disciplinary record.

To find out How to Fill your Pets Prescription click on More Information at the top. 

Product Reviews by Customers

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Browse 12 questions Browse 12 questions and 68 answers
Why did you choose this?
KV Supply Store
Way cheaper than trifexis. (We have no fleas or ticks.)
WALT M on Jul 26, 2019
I've always used this for all the dogs I've owned.
KIMBERLY B on Jun 5, 2019
Way cheaper than trifexis. (We have no fleas or ticks.)
WALT M on Jul 26, 2019
This is what I always use
JO G on Jun 26, 2019
I've always used this for all the dogs I've owned.
KIMBERLY B on Jun 5, 2019
Easy to administer, tolerated well by my dog.
Donna M on Jun 4, 2019
recommended by vet.
Pegie L on Jun 2, 2019
I have used these successfully for many years.
VIVIAN S on May 26, 2019
My Vet recommended it been using on my 5 American Pit Bulls for 9 years
Michael H on May 26, 2019
these work great .. been using this for years...and years..
TERESA W on May 20, 2019
This is what Jax has taken his whole adult life, he likes it and it works.
heidi b on May 15, 2019
Recommended by vet & have had no issues.
SHARON B on May 12, 2019
Vet recommended
CHUCK M on May 11, 2019
Vet recommend
Diane Y on May 10, 2019
vet recommended
Brenda D on Apr 28, 2019
Vet recommended
NINA M on Apr 24, 2019
My fur baby loves these and works great!
vincent L on Apr 22, 2019
Used Hartgard for the last 55 years with all my dogs.
John W on Apr 16, 2019
Prescribed by Vet
Bryant K on Apr 15, 2019
This is the product recommended by my vet.
Linda R on Apr 14, 2019
vet recommended
NINA M on Apr 9, 2019
We feel very confident about Heartgard for our pet.
GREGORY B on Apr 4, 2019
I've used this for years.
Kathleen O on Apr 3, 2019
Best price for the product!
Nancy S on Mar 30, 2019
vet recommend
PAT S on Mar 26, 2019
Economical, safe and effective.
ANN K on Mar 23, 2019
Easy to administer. Dogs will readily consume.
Lee M on Mar 12, 2019
I have been using this product for many years for my Smooth Fox Terrier dog. I have also been using this same product for my Doberman Pinscher. It works very well and I have not experienced any side effects with either dog. I am ordering from KV Supply now because their prices are less than my regular veterinarian.
Elizabeth G on Mar 9, 2019
These meds for my chi chi were recommended by my vet and have proven highly successful.
LYN N on Mar 6, 2019
Been using this for years. No side effects. Easy to give.
Katherine M on Mar 4, 2019
I have been using Heargard for the past 30 years or so and it works.
JEN M on Mar 2, 2019
I love works good
Patricia S on Feb 28, 2019
effective product
CATHY T on Feb 26, 2019
Have been using for years............
Cathy B on Feb 24, 2019
Seems to be doing the trick.
K.C. B on Feb 20, 2019
it keeps my dogs safe from heartworm and they think they are treats
Tracie C on Feb 15, 2019
Was suggested at 1st veterinarian visit 8 years ago. I am still happy with the med. Plus my dog thinks it is a yummy treat!!
DENISE E on Feb 5, 2019
have used it for years
Janet B on Feb 1, 2019
EMILY D on Jan 30, 2019
so my dog doesn't get heartworm
DENISE S on Jan 28, 2019
Been using for 10 years on many dogs and never had a problem
William L on Jan 18, 2019
Used this for years with several dogs-vets recommend
DIANNE R on Jan 12, 2019
Dog will willingly take them.
Linda G on Jan 11, 2019
Good value and customer service
PATRICIA C on Jan 6, 2019
These are easy to give -- the dogs like the flavor and take them readily, just like a treat.
LAUREN B on Jan 4, 2019
Best Prices on-line!
Linda C on Dec 1, 2018
Works well and my dogs love to the taste
Heather B on Nov 29, 2018
My dogs like them and eat them like a treat.
Jan J on Nov 23, 2018
Because I want to prevent heart worm & Heartgard is a trusted product
MICHELE C on Nov 19, 2018
Tucker enjoys these as a "treat"!
SHERRYL F on Nov 18, 2018
I have been using Heartgard for over 20 years on my different fur-babies and never have had a problem. They love the taste and eat they right up like doggie candy.
ELLEN K on Nov 16, 2018
dog has food allergies and this works for him
Grace S on Nov 11, 2018
This is what I always use
JO G on Jun 26, 2019
Easy to administer, tolerated well by my dog.
Donna M on Jun 4, 2019
Do I need a prescription ?
A shopper on Mar 30, 2018
BEST ANSWER: Yes, you need a valid prescription from your vet. You don't have to have it in hand KV will send a request to your vet.
when it will expire? is it able to last within 2 years?
luifore S on Mar 7, 2018
BEST ANSWER: Due to our constantly rotating stock, we are unable to provide the definite expiration dates that you would receive. We are committed to ensuring our Customers are sent quality, in-date items. If you were to receive an expired product, please contact our Customer Service Team at 1-844-493-6817.
Where do I mail the prescription?
Kym B on Dec 20, 2017
BEST ANSWER: How does the prescription process happen?

Pet’s Choice Pharmacy will contact your veterinarian directly to obtain the necessary information and approval to dispense the medications ordered. It is helpful to have veterinarian’s name, phone number, and fax number when you place your order so we can speed up contact process with veterinarian. After prescription is verified, your medication will be safely dispensed and shipped directly to you. If you veterinarian does not participate or support online sales, you can mail your script to us directly.

Pet’s Choice Pharmacy

814 K Street

Belleville, KS 66935 Order #
what is the difference between Heartgard and Heartgard plus?
A shopper on Jul 24, 2018
BEST ANSWER: Easy to find the answer by googling. Heartgard prevents heartworm while Heartgard Plus prevents ascarid and hookworm in addition to heartworm.
Can I order this today than send you script from my vet or can you call vet for script?
Jcssuper on Aug 30, 2018
BEST ANSWER: Please call customer service to go over prescription questions 1-800-423-8211.
I haave a price of $44.95 for 12 pk /under 25lbs. Can you match it??
Ken G on Apr 30, 2018
BEST ANSWER: I am sorry we do not price match prescription items.
i inadvertantly sent 3 rx's for my 3 dogs to the address in PA. ( for heartgard plus) will they be forwarded to Kansas? My vet does not like to be contacted when I order from catalogs. Thank you
REBECCA Z on Mar 29, 2018
BEST ANSWER: It is OK, the mail will be forwarded over to KS and the pharmacy will receive scripts.
where is this product being shipped from Heartguard?
JoAnn B on Mar 11, 2018
BEST ANSWER: Our pharmacy is located in Kansas, so this would be shipping from KS.
A shopper on Feb 10, 2018
BEST ANSWER: Heartgard Plus is used to prevent heartworm disease, treat, and control roundworms and hookworms.
Prhow much does 100 lb size cost?
A shopper on Nov 13, 2017
BEST ANSWER: At the current time a 1 month supply is $6.99, a 6 month supply is $39.95, and a 12 month supply is $76.72.
where are you located at????
peggy s on Sep 15, 2017
BEST ANSWER: Our pharmacy is located in Kansas.