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K9 Advantix II for Dogs 12-Month Supply

Regularly: $174.99
Today's savings: 25%

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In Stock. Usually Ships within 24 hours.



In Stock. Usually Ships within 24 hours.



In Stock. Usually Ships within 24 hours.

Over 55lb


In Stock. Usually Ships within 24 hours.

Shipping weight = 0.40 lb.



Product Summary:

K9 Advantix II Dog: 12-Month Supply

K9 Advantix II delivers pest protection through topical action. It protects against fleas (flea eggs and larvae), ticks, mosquitoes, biting flies, and lice. It combines imidacloprid and permethrin with insect growth regulator pyriproxyfen, which interferes with the hormone signaling of molting insects so that fleas in immature stages are unable to molt. K9 Advantix II is for monthly use on puppies (as young as 7 weeks old) and dogs. Do not use on cats.

  • Repels and kills ticks, fleas, and mosquitoes
  • Repels biting flies
  • Kills lice
  • Kills all life stages of fleas
  • Prevents development of fleas, flea eggs, and larvae
  • Kills fleas within 12 hours of initial application
  • Kills reinfesting fleas within two hours
  • Protects against ticks that may transmit organisms that can cause Lyme disease, Rocky Mountain spotted fever, Ehrlichiosis, Anaplasmosis
  • Waterproof; continues to work after a bath or weekly swimming (for optimal results, use a non-detergent shampoo)
  • One application lasts for a month
  • Can be used on puppies as young as 7 weeks old
  • Easy-to-follow application instructions on the back of every package
Item Specifications:

4-10 lb.: Green
11-20 lb.: Teal
21-55 lb.: Red
Over 55 lb.: Blue

Includes 12 applicators

Apply entire contents of tube evenly to two to three spots on the top of the back from the shoulder to the base of the tail. Monthly application.

Length of Effectiveness:
Under normal conditions, the product is effective for a month. However, in cases of severe flea infestation, retreatment may be necessary earlier than four weeks. Do not retreat more often than once every seven days. After flea control is attained, return to a monthly retreatment schedule.

8.80% Imidacloprid
44.00% Permethrin
0.44% Pyriproxyfen
46.76% other ingredients
Active ingredients work synergistically. The combination of imidacloprid with permethrin exerts a unique synergistic effect on the arthropod nervous system that is greater than either ingredient alone. Each compound acts on a different receptor area of the nerve cell.
Imidacloprid (nicotinic receptors) irreversibly opens nicotinic receptors on postsynaptic neurons, resulting in constant neuromuscular stimulation, spastic paralysis, and death.
Permethrin (sodium channels) causes prolonged sodium ion exchange across neuronal membranes, resulting in constant nerve discharge followed by spastic paralysis and death.
When both ingredients are combined, the neurotoxic stimulation is greater than that seen with either ingredient alone.

Style Item Number Model Number UPC
4-10lb 405851 001 724089203649
11-20lb 405851 002 724089203809
21-55lb 405851 003 724089204028
Over 55lb 405851 004 724089204295

Product Reviews by Customers

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Browse 1 question Browse 1 question and 17 answers
Why did you choose this?
KV Supply Store
This has worked superbly for my many dogs for years.
Shannon G on Mar 25, 2019
We have used K9 Advantix ll for years & have been happy with it.
James R on Dec 31, 2018
This has worked superbly for my many dogs for years.
Shannon G on Mar 25, 2019
Have used in past with excellent results.
Sandy L on Mar 14, 2019
We have used K9 Advantix ll for years & have been happy with it.
James R on Dec 31, 2018
Easy to use. Vet recommend.
BRENDA B on Nov 1, 2018
Effective in preventing ticks on dog.
Margaret M on Jul 25, 2018
I always use this on my two dogs and have never had a flea or a tick.
JEAN G on Jun 24, 2018
Past use on shelter animals in wooded location has proven effective. Easy to apply. This sale is very helpful. Also, saving tax on this order!
Millie H on Jun 23, 2018
We have used K9 Advantix II for years. We live in a rural area and knowing our dog is protected from ticks, fleas AND misquitoes gives us peace of mind. It is also very easy on the dog to apply especially when there is a treat involved.
PATRICIA M on Apr 17, 2018
In my opinion better than Frontline in Wisconsin where we have tons of Ticks!
GWEN C on Mar 25, 2018
After having a flea infestation using frontline, i switched to K9 advantix. Works great
RACHEL M on Mar 4, 2018
That's all my dog has ever taken for flea and tick control -- good product.
Pamela S on Jan 3, 2018
They work well.<br /> The former product I used to use, ceased to work. When I spoke with the company, they wanted 'proof' that my dogs had been on their product without a break, blah, blah, blah.
ARLENE G on Dec 27, 2017
works best for my dogs. Very happy with product and service.
MARGARET S on Nov 18, 2017
2 small dogs, supply lasts longer
Dave G on Sep 3, 2017
Have used before and am very satisfied with it
John K on Aug 4, 2017
Works great for our dogs. Never had any adverse reaction
Mary M on Jul 26, 2017
Best price anywhere!
Jason on Jul 19, 2017
Have used in past with excellent results.
Sandy L on Mar 14, 2019
Easy to use. Vet recommend.
BRENDA B on Nov 1, 2018