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Proin Chewable for Dogs

Prescription Required
From $0.35


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All medications are filled by Pet's Choice Pharmacy. More information. Can only be shipped in the United States.
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Product Summary:

Proin Chewable Tablets

This prescription item can not be shipped to Arkansas, Illinois, Iowa, Louisiana, North Carolina, Oregon or West Virginia.

(Phenylpropanolamine HCl)


Proin is a medication developed to manage urinary incontinence in dogs. Urinary incontinence, or uncontrolled leaking of urine is most frequently seen in spayed female dogs or dogs with obesity. Although less common, male dogs may also experience urinary incontinence. Proin chewable tabs are administered either as a treat or given with food.


Item Specifications:


For Use:




Use as Directed by your Veterinarian


How it works:
Proin contains the active ingredient phenylpropanolamine, an adrenergic agent that works by tightening the bladder sphincter muscle, which helps to control urine leakage.



Store at Controlled Room Temperature.


Don't give Proin with ephedrine or epinephrine, and don't give it within two weeks of using a MAOi, such as Anipryl, selegiline or a Preventic Collar. Possible side effects can occur, including restlessness, or loss of appetite, difficulty breathing, hives, and swelling of the lips, tongue, or face. If these or any other side effects occur, contact your veterinarian immediately. May cause excitability and restlessness.



Tell your veterinarian if your pet has ever had an allergic reaction to this medication. Tell your veterinarian if your pet has glaucoma, hyperthyroid disease, diabetes, heart problems or high blood pressure. Tell your veterinarian if your pet is pregnant or lactating.


Side Effects:

Stop giving Proin and contact your veterinarian immediately if your pet has an allergic reaction (difficulty breathing; swelling of the lips, tongue, face; and hives). Other side effects that may occur include restlessness, irritability, increased heart rate, increased blood pressure and loss of appetite. Continue to give the medication and contact your veterinarian. Other less serious side effects may occur. Contact your veterinarian about any side effects that seem bothersome.


Seek emergency veterinary medical treatment. Symptoms of overdose may include increased blood pressure, increased heart rate, seizures or coma.


Federal law restricts this drug to use by or on the order of a licensed veterinarian.




Style Item Number Model Number UPC
25mg 1 Tablet 496165 025 001 012CP01-25MG-TAB
25mg 60 Count 496165 025 060 012CP01-25-60 685687315489
25mg 180 Count 496165 025 180 012CP01-25-180 685687317506
50mg 1 Tablet 496165 050 001 012CP01-50MG-TAB
50mg 60 Count 496165 050 060 012CP01-50-60 685687307484
50mg 180 Count 496165 050 180 012CP01-50-180 685687307507
75mg 1 Tablet 496165 075 001 012CP01-75MG-TAB
75mg 60 Count 496165 075 060 012CP01-75-60 685687316486
75mg 180 Count 496165 075 180 685687316486
Additional Information:

Please Note: 

This prescription product or therapeutic food is fulfilled by Pet’s Choice Pharmacy, Inc. A licensed pharmacy in all states, excluding North Carolina. Pet’s Choice is actively working with North Carolina Board of Pharmacy and expect to be licensed to fill prescriptions in 2018. We can only ship to US states. 


To order prescription products or therapeutic foods must have an existing, valid veterinarian-client-patient relationship.  Prescription requests are subject to a Drug Utilization Review by a licensed pharmacist for patient safety.


All prescription products (excluding therapeutic food) are FDA approved, or EPA licensed, to be sold in the US.

Prescription products cannot be returned.  

How do you fill my pet’s prescription order?

We understand how important your pet’s health is to you. That’s why we partnered with Pet’s Choice Pharmacy, a fully accredited Vet-VIPPS national pharmacy. Located in Belleville, Kansas, Pet’s Choice Pharmacy is a trusted partner that is fully licensed to distribute pharmaceutical products in all states, excluding North Carolina. This licensing ensures that they adhere to the proper standards for handling and dispensing pet medications directly to you, at a significant savings.


How does the prescription process happen?

Pet’s Choice Pharmacy will contact your veterinarian directly to obtain the necessary information and approval to dispense the medications ordered. It is helpful to have veterinarian’s name, phone number, and fax number when you place your order so we can speed up contact process with veterinarian. After prescription is verified, your medication will be safely dispensed and shipped directly to you. If you veterinarian does not participate or support online sales, you can mail your script to us directly.

Pet’s Choice Pharmacy  

814 K Street

Belleville, KS 66935 Order #


Are we a licensed pharmacy?

The National Association of Boards of Pharmacy (NABP) has approved us as an Internet Advertiser of prescription drug-related services through its e-Advertiser Approval program. We are not a licensed pharmacy; however, we are permitted to display pet medications on our site and have prescription orders fulfilled and delivered through our trusted partner, Pet’s Choice Pharmacy, a full Vet-VIPPS accredited pharmacy. This gives you a trusted and affordable alternative to purchase the medications your beloved pets need to maintain quality of life and overall health.

If you have any medical questions about your pet, we suggest you speak with your veterinarian before administering any medication.  If you would like to speak with our pharmacy support team about your order, you can contact us directly Monday-Friday 9 am-5 pm EST at (877) 574-2267. If you veterinarian needs to fax your prescription, our fax number is (866) 787-1177.


** By law we can only accept a prescription faxed from your veterinarian or we must have the original prescription**

Product Reviews by Customers

4.9 / 5.0
20 Reviews
5 Stars
4 Stars
3 Stars
2 Stars
1 Star
4.4 / 5
August 5, 2018
1 month ago
Works great for my 5 year Samoyed!
July 30, 2018
1 month ago
Great price compared to vet pricing!
July 13, 2018
2 months ago
As expected.
July 5, 2018
1 month ago
5 / 5
Dog meds
Great fast easy
June 27, 2018
2 months ago
5 / 5
My dog has been using this product for 6 years and we have never had a problem
June 24, 2018
2 months ago
3 / 5
Works with turkey meat
My dog won’t chew them, but wrapped in a little turkey does the trick. They are effective for him.
May 25, 2018
3 months ago
5 / 5
Works great
My dog takes these easily and they work very well. Highly recommend.
May 17, 2018
3 months ago
3 / 5
Worked Wonderes
Urine leakage stopped after one dose. Started out on 3 pills daily, per vet. Reduced gradually to one pill daily.
We have to hide the pill in pill treats because she will not chew it.
May 10, 2018
12 months ago
Easy and great price.
I didn’t actually get the 75 mg but the 25 mg. Ordering was easy and prompt.
April 2, 2018
5 months ago
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Browse 2 questions Browse 2 questions and 51 answers
Why did you choose this?
KV Supply Store
BROOKE L on Aug 16, 2018
GoodRX recommended you! Saved 50% over what I have been paying at the Vet's office for years for this item! Thank you!!
Raymond V on Aug 6, 2018
BROOKE L on Aug 16, 2018
proin works great with no side effects that i can see. pricing is excellent
steve b on Aug 15, 2018
GoodRX recommended you! Saved 50% over what I have been paying at the Vet's office for years for this item! Thank you!!
Raymond V on Aug 6, 2018
1/2 the monthly price of my Vet... they recommended online purchase for long-term meds.
CHRIS B on Jul 25, 2018
This was prescribed by my vet and it has worked perfectly for 9 years.
PENELOPE B on Jul 24, 2018
prescribed by vet
Mary E on Jul 19, 2018
This works well for my Great Dane's urinary incontinence 2x/day.
Christina T on Jun 28, 2018
Helps my dog's incontinence issue.
Karen S on Jun 26, 2018
helps my senior girl with her incontinence....I usually try to do natural remedies, but the Proin has not shown any side effects and is effective for Onyx.
Jane J on Jun 23, 2018
My dog has been on this for age-related incontinence for awhile. I couldn't believe that it was so much more affordable online!
Kristen S on Jun 20, 2018
vet recommended
Dianna L on Jun 19, 2018
Prescribed by our vet
RICHARD S on Jun 15, 2018
My dog has bladder issues and it was prescribed by vet.
DEBORAH Z on Jun 9, 2018
Far cheaper than at my vets!
Sherry B on Jun 6, 2018
Prescription that she needs
Elsa D on Jun 5, 2018
Doctor's orders.
Bob B on Jun 5, 2018
It helps my dog hold her urine better.
Alessandra V on Jun 2, 2018
It is prescribed by my Vet.
Michael I on Jun 1, 2018
because my dog already uses this for urinary incontinence and it is effective and I needed a better price.
Dina H on May 24, 2018
Used Proin 50mg tabs for my dalmatian females with incontinence problems, due to spaying, for 6 years with very good results. Thought I'd try it for my Great Dane girls who have developed same problem.
Karen P on May 22, 2018
Urinary incontinence is managed with Proin for my fur baby.
Ann K on May 21, 2018
Vet recommended for my St. Bernard. Has been on for over 2 years with no problems.
TEENA I on May 21, 2018
It works so well for my pup!
LAURIE B on May 15, 2018
incontinence issuses
Blair f on May 9, 2018
our vet recommended it
Kelly B on May 7, 2018
Dog has incontinence and these help with leaks so our daily life is more fun.
Elizabeth N on May 1, 2018
It's is prescribed for incontinence in our female due to early spay.
Quinton B on Apr 25, 2018
My puppy has had UTIs and urinary incontinence her entire life (she'll be 2 in May). Proin (25mg 2x a day) has definitely helped stem the flow, although she still has occasional, yet much smaller, accidents. The vet and I think it's best to avoid the trauma of surgery, so we'll be using these a bit longer so see if they'll be able to help completely clear her problem.
Alison K on Apr 21, 2018
Works very well for controlling our spayed Newf's bladder issues
LEIGH B on Apr 11, 2018
Schnauzers have a propensity for urinary problems. This product keeps her in check. Also, KC pricing is unbeatable.
Mary E on Apr 8, 2018
Recommended by Vet. Been using for 6 yrs on large female.
Jeff on Apr 5, 2018
Older Dobergal..leaks, and this is what Vet perscribed
Virginia F on Apr 2, 2018
It really helps my dog with her leaking problem.
Jerilyn C on Apr 2, 2018
Prescribed by the Vet. Our dog doesn't have accidents in the home so I figure it works.
Bob B on Mar 27, 2018
My female 70 pound Doberman has had leakage problems when she sleeps. After starting Proin, she no longer pees on my couch! Yahhhhhhh
RITA A on Mar 25, 2018
This medication has helped our 11 yr old Great Dane with her incontinence. She hasn't had any accidents since she has been on it. Wonderful medication. Thank you.
Gloria S on Mar 8, 2018
vet recommended
Debra W on Mar 8, 2018
My dog has spay incontinence and this prevents her from leaking....thank goodness!
DAYNA S on Feb 25, 2018
This product makes a huge difference for our spayed Newfoundland girl. She leaks terribly if she doesn't take it. It's nice to have it, rather than using an antihistamine, as we did in the past.
LEIGH B on Feb 21, 2018
Prescription medication much cheaper than purchasing at the vet's office
Michelle O on Feb 17, 2018
Best price on internet
Billie W on Feb 15, 2018
This medication has helped Rain avoid urinary leakage.
stephen r on Feb 10, 2018
It works our Newfie's been on it fro 11 years!
Gary B on Feb 7, 2018
because it costs less
nathaniel o on Feb 6, 2018
she has a condition and this helps
James W on Feb 1, 2018
It is cheaper than the vet
Helen S on Jan 25, 2018
vet prescription for leaky bladder
LINDA G on Jan 24, 2018
Prescribed by vet and KV has best price
Paula D on Jan 23, 2018
My dog is 8 years old and has been on this medication for 7 years. She has not had a problem with urinary incontinence since being on this medication!
Janet L on Jan 22, 2018
vet prescribed eliminates leaking!!
judith c on Jan 22, 2018
proin works great with no side effects that i can see. pricing is excellent
steve b on Aug 15, 2018
1/2 the monthly price of my Vet... they recommended online purchase for long-term meds.
CHRIS B on Jul 25, 2018
A shopper on Nov 13, 2017